Cold/long-term missing person cases continue to be a matter of great concern for the public and police. Scholars have attempted to study the issue of missing persons more broadly, using research from across regions to understand this phenomenon. However, there has been little study of how relevant research from different regions is to other areas and little examination of cold/long-term missing person cases. Given these two considerations – these cases being of great concern but understudied and the blending of research findings from different regions – this study presents first insights on cold/long-term missing person cases from England and Wales versus Canada through a comparative examination. From this, we offer key recommendations that either region may benefit from for enhancing police response. We also highlight the applicability of research from each region, discussing the implications of different police systems, processes, and challenges.